Conformational Switches Regulate Clathrin Mediated Endocytosis

Conformational Switches Regulate Clathrin Mediated Endocytosis

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This work suggests a general mechanism of numerous conformational switches being flipped to regulated clathrin mediated endocytosis.Homodimers of hip1 and hip1R were mixed at 1:1 ratio then a thermal denaturation profile was obtained (corresponding to melting step 1 in the diagram. open circles ). The mixture of denatured proteins was allowed to anneal slowly back toanbsp;...


Title:Conformational Switches Regulate Clathrin Mediated Endocytosis
Author: Jeremy D. Wilbur
Publisher:ProQuest - 2008
ISBN-13:

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